Hyperbaric Oxygen-Induced Attenuation of Hemorrhagic Transformation After Experimental Focal Transient Cerebral Ischemia
نویسندگان
چکیده
منابع مشابه
Hyperbaric oxygen-induced attenuation of hemorrhagic transformation after experimental focal transient cerebral ischemia.
BACKGROUND AND PURPOSE An increased risk of hemorrhagic transformation is a major factor limiting the use of tissue plasminogen activator for stroke. Increased hemorrhagic transformation is also found in animals undergoing transient focal cerebral ischemia with hyperglycemia; this study examined whether hyperbaric oxygen (HBO) could reduce such hemorrhagic transformation in a rat model. METHO...
متن کاملNeuroprotection by Hyperbaric Oxygenation After Experimental Focal Cerebral Ischemia
Nils Henninger, Harald Müller, Ulrich Carl, Shinya Toyokuni, Clemens Sommer and Stefan Wolf-Ruediger Schäbitz, Holger Schade, Sabine Heiland, Rainer Kollmar, Jürgen Bardutzky, Monitored by MRI Neuroprotection by Hyperbaric Oxygenation After Experimental Focal Cerebral Ischemia Print ISSN: 0039-2499. Online ISSN: 1524-4628 Copyright © 2004 American Heart Association, Inc. All rights reserved. is...
متن کاملHyperbaric oxygen reduces blood-brain barrier damage and edema after transient focal cerebral ischemia.
BACKGROUND AND PURPOSE Hyperbaric oxygen (HBO) has been shown to protect the brain parenchyma against transient focal cerebral ischemia, but its effects on the ischemic microcirculation are largely unknown. We examined the potential of HBO to reduce postischemic blood-brain barrier (BBB) damage and edema. METHODS Wistar rats and C57/BL6 mice underwent occlusion of the middle cerebral artery (...
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Introduction: Cerebral ischemia is one of the most common causes of death in human populations in the industrial communities. The need for animal models is inevitable to study the pathophysiology and treatment of cerebral ischemia in human. The current study aimed at evaluating the strengths and weaknesses of different techniques used to create ischemia in previous studies and optimizing the tr...
متن کاملHyperbaric oxygen preconditioning attenuates hyperglycemia enhanced hemorrhagic transformation after transient MCAO in rats
BACKGROUND Hemorrhagic transformation (HT) can be a devastating complication of ischemic stroke. Hyperbaric oxygen preconditioning (HBO-PC) has been shown to improve blood-brain barrier (BBB) permeability in stroke models. The purpose of this study is to examine whether HBO-PC attenuates HT after focal cerebral ischemia, and to investigate whether the mechanism of HBO-PC against HT includes up-...
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ژورنال
عنوان ژورنال: Stroke
سال: 2007
ISSN: 0039-2499,1524-4628
DOI: 10.1161/01.str.0000259660.62865.eb